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What a Proper Testosterone Check Looks Like

A single blood draw in the afternoon is not what the guidelines describe.

Picture a man named Greg, 61. He has felt tired for a year. A friend told him to "get his testosterone checked." He is not sure what a good check involves, so he asks a few questions before he goes.

What the guidelines ask for

Two major guidelines describe the same basic steps.

Step American Urological Association Endocrine Society
Symptoms or signs first Yes Yes
Early-morning blood test Two separate tests Fasting morning test, repeated to confirm
Cutoff for low 300 ng/dL total testosterone Consistently low level
Routine testing for everyone No No, they advise against screening

The Urological Association guideline was published in 2018 and confirmed as valid in 2024. The Endocrine Society guideline is from 2018.

What this means in practice

A single blood draw in the afternoon is not what the guidelines describe. Testosterone falls through the day, so a late test can read low in a man whose morning level is fine. A second reading guards against acting on one low number.

A good visit could also include a talk about sleep, alcohol, weight, medicines and mood, since those can cause the same symptoms.

Questions Greg could ask

You could…

  • Ask for the first blood draw before 10 a.m.

  • Bring your written list of symptoms and when they began.

  • Ask what the plan is if the result is normal.

Have you had a testosterone check? What did the doctor ask you? Share it here. Another reader may be deciding whether to go.

Sources: American Urological Association guideline on testosterone deficiency (2018, validity confirmed 2024); Endocrine Society guideline (2018). Figures are estimates for planning, based on public data.

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